BDBM50319690 1-(4-(1-benzyl-1,4-dihydropyrazolo[4,3-d]imidazol-5-yl)phenyl)-3-(3-chloro-5-(trifluoromethyl)phenyl)urea::CHEMBL1086486

SMILES FC(F)(F)c1cc(Cl)cc(NC(=O)Nc2ccc(cc2)-c2nc3c[nH]n(Cc4ccccc4)c3n2)c1

InChI Key InChIKey=NVYZZGGUXSQWFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319690   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319690(1-(4-(1-benzyl-1,4-dihydropyrazolo[4,3-d]imidazol-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human cRAF using [33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed