BDBM50319829 1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine::CHEMBL1083427

SMILES Fc1cccc(c1)C(Cc1ccccc1OC(F)(F)F)N1CCNCC1

InChI Key InChIKey=LRKGVRWKYSKWQW-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319829   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319829(1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)pheny...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319829(1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)pheny...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319829(1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)pheny...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319829(1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)pheny...)
Affinity DataIC50: 6.11E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed