BDBM50319953 (1S,4S)-2-methyl-5-(5-phenylpyrimidin-2-yl)-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1085581

SMILES CN1C[C@@H]2C[C@H]1CN2c1ncc(cn1)-c1ccccc1

InChI Key InChIKey=OODPDBZXZQDRMJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319953   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319953((1S,4S)-2-methyl-5-(5-phenylpyrimidin-2-yl)-2,5-di...)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at human alpha7 nACHR expressed in Xenopus oocyte assessed as activation of current by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319953((1S,4S)-2-methyl-5-(5-phenylpyrimidin-2-yl)-2,5-di...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319953((1S,4S)-2-methyl-5-(5-phenylpyrimidin-2-yl)-2,5-di...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed