BDBM50319972 CHEMBL1082977::N-benzyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-amine

SMILES CC1CCN(CC1)c1nccc(NCc2ccccc2)n1

InChI Key InChIKey=VAPRIZYIVOPQLU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319972   

TargetAcetylcholinesterase(Electric eel)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319972(N-benzyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-ami...)
Affinity DataIC50: 390nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319972(N-benzyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-ami...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319972(N-benzyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-ami...)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human AChE incubated with compounf for 5 mins before addition of substrate acetylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319972(N-benzyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-ami...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of equine BChE incubated with compounf for 5 mins before addition of substrate S-butyrylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed