BDBM50319979 2-morpholino-N-(naphthalen-1-ylmethyl)pyrimidin-4-amine::CHEMBL1084211

SMILES C(Nc1ccnc(n1)N1CCOCC1)c1cccc2ccccc12

InChI Key InChIKey=IWVKLFVNDFNPIF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319979   

TargetAcetylcholinesterase(Electric eel)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319979(2-morpholino-N-(naphthalen-1-ylmethyl)pyrimidin-4-...)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319979(2-morpholino-N-(naphthalen-1-ylmethyl)pyrimidin-4-...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319979(2-morpholino-N-(naphthalen-1-ylmethyl)pyrimidin-4-...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of equine BChE incubated with compounf for 5 mins before addition of substrate S-butyrylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319979(2-morpholino-N-(naphthalen-1-ylmethyl)pyrimidin-4-...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human AChE incubated with compounf for 5 mins before addition of substrate acetylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed