BDBM50320127 CHEMBL1085565::N-(3-(1-(2-(4-((N-benzyl-4-chlorophenylsulfonamido)methyl)benzoyl)hydrazinyl)ethyl)phenyl)acetamide

SMILES CC(=O)Nc1cccc(c1)C(C)=NNC(=O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=LDWBOMUFSWMQIR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320127   

TargetC-X-C chemokine receptor type 3(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50320127(N-(3-(1-(2-(4-((N-benzyl-4-chlorophenylsulfonamido...)
Affinity DataKi:  211nMAssay Description:Displacement of labeled ITAC from CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50320127(N-(3-(1-(2-(4-((N-benzyl-4-chlorophenylsulfonamido...)
Affinity DataKi:  348nMAssay Description:Displacement of labeled IP10 from CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50320127(N-(3-(1-(2-(4-((N-benzyl-4-chlorophenylsulfonamido...)
Affinity DataIC50: 538nMAssay Description:Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50320127(N-(3-(1-(2-(4-((N-benzyl-4-chlorophenylsulfonamido...)
Affinity DataKi:  6.50E+3nMAssay Description:Antagonist activity at CXCR3 (unknown origin) assessed as reduction in CXCL10 induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed