BDBM50320364 (4-(4-phenylphthalazin-1-yl)piperazin-1-yl)(thiazol-2-yl)methanone::CHEMBL1083104

SMILES O=C(N1CCN(CC1)c1nnc(-c2ccccc2)c2ccccc12)c1nccs1

InChI Key InChIKey=NZDDSVZRFYCJOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320364   

TargetSmoothened homolog(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50320364((4-(4-phenylphthalazin-1-yl)piperazin-1-yl)(thiazo...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human SMO expressed in HEPM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed