BDBM50320418 4-(4-(4-(2,4-dimethylphenyl)piperazin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide::CHEMBL1084217

SMILES Cc1ccc(N2CCN(CC2)c2ccc(cc2)S(=O)(=O)C2(CCOCC2)C(=O)NO)c(C)c1

InChI Key InChIKey=GWRXKVPUXYYCMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50320418   

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320418(4-(4-(4-(2,4-dimethylphenyl)piperazin-1-yl)phenyls...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320418(4-(4-(4-(2,4-dimethylphenyl)piperazin-1-yl)phenyls...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed