BDBM50320444 1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL1082318

SMILES Cc1cccc(N2CCN(CC2)C(=O)C2CCN(CC2)c2ccc(cc2)S(=O)(=O)C2(CCN(CC2)C2CC2)C(=O)NO)c1C

InChI Key InChIKey=HWZVYNMATDDRGV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50320444   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 28nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 550nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed