BDBM50320446 CHEMBL1085510::[N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroisoxazolo[4,3-c]quinoline

SMILES CN1CC2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12

InChI Key InChIKey=GHPKBFZQNLPFFZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50320446   

TargetAlpha-2A adrenergic receptor(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50320446([N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]rauwolscine from adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50320446([N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]rauwolscine from adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50320446([N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]paroxetine from 5HTT receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed