BDBM50320876 4-(4-Chlorophenyl)-7,7-dimethyl-2-phenyl-4,6,7,8-tetrahydroquinolin-5(1H)-one::CHEMBL1164073

SMILES CC1(C)CC(=O)C2C(C=C(N=C2C1)c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=FCDCXWUZDFYLGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320876   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320876(4-(4-Chlorophenyl)-7,7-dimethyl-2-phenyl-4,6,7,8-t...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed