BDBM50321115 2-(4-Methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one::CHEMBL1164862

SMILES Cc1ccc(cc1)-c1nc2ccccc2c(=O)n1-c1nccs1

InChI Key InChIKey=OFOCYFHKXGXVAH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321115   

TargetThermolysin(Bacillus thermoproteolyticus)
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50321115(2-(4-Methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-...)
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin after 15 mins by microplate fluorescence analysis in presence of 0.1 M substrate FaGLaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50321115(2-(4-Methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-...)
Affinity DataKi:  5.93E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin after 15 mins by microplate fluorescence analysis in presence of 0.5 to 2 mM substrate FaGLaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed