BDBM50321178 CHEMBL1163644::rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4-fluorophenyl)propan-1-one

SMILES [O-][N+](=O)c1ccc(NC(CC(=O)c2ccc(F)cc2)c2cccc(F)c2)cc1

InChI Key InChIKey=DYJWFOYAGMZBFA-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321178   

TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataIC50: 805nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed