BDBM50322250 4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-3-yl)-methyl)piperidin-4-ol oxalate::CHEMBL1173711

SMILES OC1(CCN(Cc2c[nH]c3cccc(OCCF)c23)CC1)c1ccc(Br)cc1

InChI Key InChIKey=ORBZGAXKHHPTOD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322250   

TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322250(4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-...)
Affinity DataKi:  27.7nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322250(4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-...)
Affinity DataKi:  668nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322250(4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-...)
Affinity DataKi:  849nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322250(4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-...)
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed