BDBM50322326 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-methoxyphenyl)acrylate::CHEMBL1173014

SMILES COc1cccc(\C=C\C(=O)OCCn2c(C)ncc2[N+]([O-])=O)c1

InChI Key InChIKey=NYLURTZYLDYWMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322326   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322326((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322326((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed