BDBM50322334 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-methoxyphenyl)acrylate::CHEMBL1173713

SMILES COc1ccc(\C=C\C(=O)OCCn2c(C)ncc2[N+]([O-])=O)cc1

InChI Key InChIKey=BUHRXTFCHFVRAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322334   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322334((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322334((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50322334((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4...)
Affinity DataIC50: 3.11E+4nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed