BDBM50322360 5-bromoisoquinolin-1(2H)-one::CHEMBL1173518::US12338238, Example 33

SMILES Brc1cccc2c1cc[nH]c2=O

InChI Key InChIKey=UKIWLFJYNMJPEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322360   

TargetPoly [ADP-ribose] polymerase 1(Human)
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50322360(5-bromoisoquinolin-1(2H)-one | CHEMBL1173518 | US1...)
Affinity DataIC50: 270nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM50322360(5-bromoisoquinolin-1(2H)-one | CHEMBL1173518 | US1...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2025
Entry Details
Go to US Patent