BDBM50322443 4-{4-[2-(2-Dimethylamino-ethoxy)-5-methanesulfonyl-benzoyl]-piperazin-1-yl}-3-fluorobenzonitrile::CHEMBL1173030

SMILES CN(C)CCOc1ccc(cc1C(=O)N1CCN(CC1)c1ccc(cc1F)C#N)S(C)(=O)=O

InChI Key InChIKey=SCUQFNPEPJLVKL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322443   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322443(4-{4-[2-(2-Dimethylamino-ethoxy)-5-methanesulfonyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human GlyT1b expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322443(4-{4-[2-(2-Dimethylamino-ethoxy)-5-methanesulfonyl...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human GlyT2 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed