BDBM50322880 CHEMBL1210432::N-((2S,3R)-4-(cyclohexylamino)-3-hydroxy-1-phenylbutan-2-yl)-3-(N-phenylmethylsulfonamido)benzamide

SMILES CS(=O)(=O)N(c1ccccc1)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CCCCC1

InChI Key InChIKey=FEOZKBJQAROHID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322880   

TargetCathepsin D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322880(N-((2S,3R)-4-(cyclohexylamino)-3-hydroxy-1-phenylb...)
Affinity DataIC50: 193nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322880(N-((2S,3R)-4-(cyclohexylamino)-3-hydroxy-1-phenylb...)
Affinity DataIC50: 243nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322880(N-((2S,3R)-4-(cyclohexylamino)-3-hydroxy-1-phenylb...)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed