BDBM50322894 CHEMBL1210341::N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-phenylbutan-2-yl)-3-(N-(2-methoxyphenyl)methylsulfonamido)benzamide

SMILES COc1ccccc1N(c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN[C@@H](C)C(=O)NC1CCCCC1)S(C)(=O)=O

InChI Key InChIKey=LWYYRFSTHDYJTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322894   

TargetBeta-secretase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322894(N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-...)
Affinity DataIC50: 126nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322894(N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-...)
Affinity DataIC50: 405nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322894(N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed