BDBM50322921 6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitrile::CHEMBL1209772

SMILES CCOc1ccc(cc1C(F)(F)F)-c1cccc(n1)C#N

InChI Key InChIKey=JZVLBECHGUMCQS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322921   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed