BDBM50322936 1-(4-chlorophenyl)-N-(3-cyanophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210506

SMILES Fc1cccc(c1)N1C(c2ccc(Cl)cc2)C2(CCN(CC2)C(=O)Nc2cccc(c2)C#N)C1=O

InChI Key InChIKey=JNLCJXJHIHGZEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322936   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322936(1-(4-chlorophenyl)-N-(3-cyanophenyl)-2-(3-fluoroph...)
Affinity DataIC50: 183nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322936(1-(4-chlorophenyl)-N-(3-cyanophenyl)-2-(3-fluoroph...)
Affinity DataIC50: 183nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed