BDBM50322965 1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isopropyl-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210081

SMILES CC(C)N1CC2(CCN(CC2)C(=O)Nc2cc(F)cc(F)c2)C1c1ccc(Cl)cc1

InChI Key InChIKey=DGFHXAOEKNNJGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322965   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322965(1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isopro...)
Affinity DataIC50: 138nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322965(1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isopro...)
Affinity DataIC50: 328nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed