BDBM50322992 CHEMBL1210030::N-(1-((2-ethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)-5-methylnicotinamide

SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1-c1ccc(F)cc1

InChI Key InChIKey=GTUKZINNLXNLAX-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322992   

TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322992(N-(1-((2-ethoxy-4'-fluorobiphenyl-4-yl)methyl)pipe...)
Affinity DataKi:  4.90nMAssay Description:Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322992(N-(1-((2-ethoxy-4'-fluorobiphenyl-4-yl)methyl)pipe...)
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed