BDBM50323092 2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9-ethyl-9H-purine-6-carbonitrile::CHEMBL1209532

SMILES CCOc1ccc(cc1C(F)(F)F)-c1nc(C#N)c2ncn(CC)c2n1

InChI Key InChIKey=LZCDRZUIRZENCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323092   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323092(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9-ethyl-9H-...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323092(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9-ethyl-9H-...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed