BDBM50323356 6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-isopropoxymethyl-6,7-dihydro-5-thia-2,3a,6-triaza-indene 5,5-dioxide::CHEMBL1209694

SMILES CC(C)OCC1n2cncc2CN([C@@H](C)c2ccc(Cl)cc2)S1(=O)=O

InChI Key InChIKey=NHRLPAVZBKIQPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323356   

TargetCytochrome P450 11B2, mitochondrial(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323356(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-isopropoxymeth...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant CYP11B2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323356(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-isopropoxymeth...)
Affinity DataIC50: 222nMAssay Description:Inhibition of human recombinant CYP11B1 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323356(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-isopropoxymeth...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human CYP3A4-mediated testosterone oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed