BDBM50323410 1-(4-methoxyphenyl)-4-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)piperazine::CHEMBL1209099

SMILES COc1ccc(cc1)N1CCN(Cc2cnn(c2C)-c2ccccc2)CC1

InChI Key InChIKey=ZDZDDOQABKBUSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323410   

TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323410(1-(4-methoxyphenyl)-4-((5-methyl-1-phenyl-1H-pyraz...)
Affinity DataIC50: 126nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323410(1-(4-methoxyphenyl)-4-((5-methyl-1-phenyl-1H-pyraz...)
Affinity DataIC50: 105nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed