BDBM50323723 2-nitrophenyl 3-(4-hydroxy-3,5-dimethylstyryl)benzoate::CHEMBL1213030

SMILES Cc1cc(\C=C\c2cccc(c2)C(=O)Oc2ccccc2[N+]([O-])=O)cc(C)c1O

InChI Key InChIKey=SQNQOBGKYCCYBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323723   

TargetTransthyretin(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323723(2-nitrophenyl 3-(4-hydroxy-3,5-dimethylstyryl)benz...)
Affinity DataIC50: 2.26E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed