BDBM50323775 CHEMBL1214060::N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)nortropane

SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(C)cc1)N2C\C=C\CF

InChI Key

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50323775   

TargetSodium-dependent serotonin transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataKi:  147nMAssay Description:Displacement of [3H](R,S)-citalopram HBr from human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50323775(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataKi:  265nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed