BDBM50323898 1,1,1-trifluoro-N-(3-(((3S,4R)-4-(hydroxymethyl)-2,2-dimethyl-7-((6-methylquinolin-2-yl)methoxy)chroman-3-yl)methyl)-4-methoxyphenyl)methanesulfonamide::CHEMBL1214531

SMILES COc1ccc(NS(=O)(=O)C(F)(F)F)cc1C[C@H]1[C@@H](CO)c2cc(OCc3ccc4ccc(C)cc4n3)ccc2OC1(C)C

InChI Key InChIKey=CVDSOAXGLZLWEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323898   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323898(1,1,1-trifluoro-N-(3-(((3S,4R)-4-(hydroxymethyl)-2...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed