BDBM50323925 (E)-3-(Thiazol-4-ylethynyl)cyclohex-2-enone O-2-(2-fluoroethoxy)ethyl oxime::CHEMBL1214362

SMILES FCCOCCO\N=C1/CCCC(=C1)C#Cc1cscn1

InChI Key InChIKey=SLTHNPGPSDJKCB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323925   

TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL
LigandPNGBDBM50323925((E)-3-(Thiazol-4-ylethynyl)cyclohex-2-enone O-2-(2...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed