BDBM50323975 CHEMBL1214176::N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-N,2-dimethyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide

SMILES CCCn1c(C)c(cc1-c1ccccc1)C(=O)N(C)CCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=IEWFOUIWCVNBEV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323975   

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323975(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323975(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323975(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 163nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
LigandPNGBDBM50323975(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 700nMAssay Description:Displacement of [3H] astemizole from human recombinant ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed