BDBM50324085 CHEMBL1214892::N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)piperazine

SMILES CCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key InChIKey=XPJMTJRBFHPHRB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324085   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324085(N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)pip...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324085(N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)pip...)
Affinity DataKi:  53.8nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324085(N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)pip...)
Affinity DataKi:  655nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324085(N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)pip...)
Affinity DataKi:  4.72E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324085(N-(Benzofuran-2-ylmethyl)-N'-(4'-propoxybenzyl)pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed