BDBM50324095 CHEMBL1215037::N-(Benzofuran-2-ylmethyl)-N'-(2'-propoxybenzyl)piperazine

SMILES CCCOc1ccccc1CN1CCN(Cc2cc3ccccc3o2)CC1

InChI Key InChIKey=YLTFHKSBGVTTMX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324095   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324095(N-(Benzofuran-2-ylmethyl)-N'-(2'-propoxybenzyl)pip...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324095(N-(Benzofuran-2-ylmethyl)-N'-(2'-propoxybenzyl)pip...)
Affinity DataKi:  116nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324095(N-(Benzofuran-2-ylmethyl)-N'-(2'-propoxybenzyl)pip...)
Affinity DataKi:  2.46E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324095(N-(Benzofuran-2-ylmethyl)-N'-(2'-propoxybenzyl)pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed