BDBM50324208 (+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(4-fluorophenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid::(3S,3aS)-2-(3-Chloro-4-cyanophenyl)-3-(4-fluorophenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid::CHEMBL1215329

SMILES OC(=O)c1ccc2C3=NN([C@@H]([C@@H]3CCc2c1)c1ccc(F)cc1)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=ABRSQONXUKMPNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324208   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324208((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(4-f...)
Affinity DataIC50: 223nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324208((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(4-f...)
Affinity DataIC50: 223nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed