BDBM50324226 (3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-2,3,3a,4-tetrahydrochromeno[4,3-c]pyrazole-7-carboxylic Acid::CHEMBL1215627

SMILES Cc1cc(ccc1C#N)N1N=C2[C@H](OCc3cc(ccc23)C(O)=O)[C@@H]1C1CCCC1

InChI Key InChIKey=SSZMAARPGXYFMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324226   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)
Affinity DataIC50: 1.88E+3nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed