BDBM50324227 4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]benzoic Acid::CHEMBL1214839

SMILES OC(=O)c1ccc(cc1)C1=NN([C@H](C1)c1ccc(F)cc1)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=BAUZWUSZPXPFMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324227   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)
Affinity DataIC50: 8.92E+3nMAssay Description:Antagonist activity at androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)
Affinity DataIC50: 2.08E+3nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed