BDBM50324686 CHEMBL1221770::N-(4-(naphthalen-1-ylamino)quinazolin-6-yl)acrylamide

SMILES C=CC(=O)Nc1ccc2ncnc(Nc3cccc4ccccc34)c2c1

InChI Key InChIKey=KQICINWXQDDNKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324686   

TargetTyrosine-protein kinase Fyn(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50324686(N-(4-(naphthalen-1-ylamino)quinazolin-6-yl)acrylam...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of Fyn expressed in Escherichia coli C43 by radioactive phosphotransfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50324686(N-(4-(naphthalen-1-ylamino)quinazolin-6-yl)acrylam...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of c-src in by radioactive phosphotransfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed