BDBM50324738 3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propanenitrile::CHEMBL1222281

SMILES O=C1S\C(=C/c2ccccc2)C(=O)N1CCC#N

InChI Key InChIKey=ROMFZBBIJSONPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324738   

TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed