BDBM50324966 3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)ethoxy)benzoyl)benzo[b]thiophen-6-yl)acrylic acid::CHEMBL1222036

SMILES OC(=O)\C=C\c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(sc2c1)-c1ccc(O)cc1

InChI Key InChIKey=IBSQBBOGPJGCFE-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324966   

TargetEstrogen receptor(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at human wild type ERbeta expressed in human HeLa cells co-expressing AP-1 assessed as inhibition of raloxifene-induced transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataEC50:  150nMAssay Description:Antagonist activity at human wild type ERbeta expressed in human HeLa cells co-expressing AP-1 assessed as inhibition of transactivation activity by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human wild type ERbeta expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed