BDBM50325012 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(2-methyl-2H-indazol-6-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223077

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc4cn(C)nc4c3)C(=O)c2c1

InChI Key InChIKey=ILWKYNOKRNHWCN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325012   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325012((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataKi:  2nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed