BDBM50325065 1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperazin-1-yl)methyl)phenyl)methyl)-4-cyclobutyl-1,4-diazepane::CHEMBL1223158

SMILES CN1CCN(Cc2ccc(cc2)C(N2CCCN(CC2)C2CCC2)c2nnnn2Cc2ccccc2)CC1

InChI Key InChIKey=KOIKIOIHIGLQAU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325065   

TargetHistamine H3 receptor(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50325065(1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperaz...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50325065(1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperaz...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50325065(1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperaz...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50325065(1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperaz...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed