BDBM50325152 5-methyl-8-(4-(methylsulfinyl)phenyl)-[1,2,4]triazolo[4,3-a]quinolin-1(2H)-one::CHEMBL1223244

SMILES Cc1cc2n[nH]c(=O)n2c2cc(ccc12)-c1ccc(cc1)S(C)=O

InChI Key InChIKey=AAJXFZWRBGYHQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325152   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50325152(5-methyl-8-(4-(methylsulfinyl)phenyl)-[1,2,4]triaz...)
Affinity DataIC50: 90nMAssay Description:Inhibition of His6-CHK1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed