BDBM50325862 CHEMBL1224067::endo-4-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)picolinamide

SMILES NC(=O)c1cc(O[C@@H]2C[C@@H]3CC[C@H](C2)N3Cc2ccccc2)ccn1

InChI Key InChIKey=KDYAEPCFPWDFLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325862   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325862(endo-4-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325862(endo-4-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-...)
Affinity DataIC50: 1.42E+4nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in HEK cells assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed