BDBM50326068 (E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylthio)-1-(4-fluorophenyl)prop-2-en-1-one::CHEMBL1242760

SMILES [O-][N+](=O)c1cc(\C=C(\SCc2ccc(F)cc2)C(=O)c2ccc(F)cc2)ccc1F

InChI Key InChIKey=MUMWSXHTWWVJHP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326068   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Temple University

Curated by ChEMBL

LigandBDBM50326068((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/11/2011
Entry Details Article
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