BDBM50326121 CHEMBL1242520::{5-[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-yl]-4-methyl-thiazol-2-yl}-carbamic acid ethyl ester

SMILES CCOC(=O)Nc1nc(C)c(s1)-c1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1

InChI Key InChIKey=XPXJVVOSWOEDEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326121   

TargetTranscription factor Jun(Human)
B.V. Patel Pharmaceutical Education and Research Development Centre

Curated by ChEMBL
LigandPNGBDBM50326121({5-[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed