BDBM50326169 (S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2-enyl)benzyl)-3-(4-hydroxyphenyl)-5-oxo-2,5-dihydrofuran-2-carboxylate::CHEMBL1242973

SMILES [#6]-[#8]-[#6](=O)[C@@]1([#6]-c2ccc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2)[#8]-[#6](=O)-[#6](=O)-[#6]1-c1ccc(-[#8])cc1

InChI Key InChIKey=PPHDTKRVBHQPGT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50326169   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human GST-CDK1/cyclin B1 expressed in baculovirus using [gamma-33P]ATP after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, PfmrkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Leibniz-Institute For Natural Product Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DYRK1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed