BDBM50326417 3-(4-fluorophenyl)-N-(2-methoxyethyl)imidazo[1,2-b]pyridazin-6-amine::CHEMBL1243376::US10688093, Compound 229_0033_0339::US11701353, Compound 229_0033_0339

SMILES COCCNc1ccc2ncc(-c3ccc(F)cc3)n2n1

InChI Key InChIKey=LDGQYCUDRXOSIZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326417   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL

LigandBDBM50326417(3-(4-fluorophenyl)-N-(2-methoxyethyl)imidazo[1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/11/2011
Entry Details Article
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TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent

LigandBDBM50326417(3-(4-fluorophenyl)-N-(2-methoxyethyl)imidazo[1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 4.00E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL