BDBM50326681 3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide::CHEMBL1254685

SMILES C[C@H]1CN(CCC(=O)Nc2ccccc2)[C@@H]2Cc3ccc(O)cc3[C@]1(C)C2

InChI Key InChIKey=ZQHXSPSYXBMABX-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326681   

TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50326681(3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tet...)
Affinity DataIC50: 12nMAssay Description:Agonist activity at delta opioid expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50326681(3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tet...)
Affinity DataIC50: 4.80nMAssay Description:Agonist activity at mu opioid expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50326681(3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tet...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]DAMGO from Sprague-Dawley rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50326681(3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tet...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DPDPE from Sprague-Dawley rat delta opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50326681(3-[(2R,6R,11R)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tet...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]U69593 from Sprague-Dawley rat kappa opioid receptor in guinea pig cerebella by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed