BDBM50327095 1-(2-Chloro-4-{[6-(methoxymethyl)-5-methyl-5H-pyrrolo [3,2-d]pyrimidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]-urea::CHEMBL1253917

SMILES COCc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(Cl)c3)c2n1C

InChI Key InChIKey=OGXAOOVPORQDLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327095   

TargetVascular endothelial growth factor receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327095(1-(2-Chloro-4-{[6-(methoxymethyl)-5-methyl-5H-pyrr...)
Affinity DataIC50: 14nMAssay Description:Inhibition of His-tagged human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327095(1-(2-Chloro-4-{[6-(methoxymethyl)-5-methyl-5H-pyrr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged human FGFR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed